Posters session

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Medical Countermeasures


On-field validation of the rapid diagnostic test Ebola eZYSCREEN® - Laurent BELLANGER

Biological effects of alumina nanoparticles / hydrochloric acid mixtures mimicking combustion aerosols from solid composite propellants on human pulmonary A549 alveolar epithelial cells – Alexandra BOURGOIS

Procaryotic expression of human butyrylcholinesterase: a new tool for the development of affordable nerve agents bioscavengers – Xavier BRAZZOLOTTO

In vivo efficacy assessment of novel uncharged reactivators of NOP-inhibited acetylcholinesterase in Mouse compared to pralidoxime – André-Guilhem CALAS

Effect of anthrax edema toxin – Belinda DESRUES

Design, synthesis and in vitro evaluation of a promising new class of bifunctional uncharged hybrid reactivators for nerve agent-inhibited human acetylcholinesterase – José DIAS

A unique preclinical core facility structure to study in non-human primates: intoxications, infections and to test and/or validate vaccines and medical countermeasures efficacy – Frédéric DUCANCEL

Modified Vaccinia Lister (MVL), a safe and easy to produce vector for human or veterinary vaccines –
Audrey FERRIER-REMBERT

Development of monoclonal antibodies against Sudan Ebolavirus for detection, diagnostic and therapy –
Fabrice GALLAIS

Systems Biology networks/pathways: Comparison at 72 h and 75 days post exposure to Soman in rats –
Aarti GAUTAM

A novel CWA vapor inhalation exposure system for nose-only delivery with rodents – Sébastien GRAZIANI

Specific polyclonal F(ab’)2 immunoglobulin fragments; in vitro characterization and in vivo effectiveness in post-exposure treatment against Zaire Ebola virus in mice – Cécile HERBRETEAU

Structure-based drug design of new compounds targeting the protein-protein interfaces of the vaccinia virus DNA polymerase holoenzyme – Frédéric ISENI

Efficiency of multiple administrations of an HI-6 dimethanesulfonate, atropine sulfate and avizafone chlorhydrate combined treatment in Russian VX-intoxicated cynomolgus monkeys – Nina JAFFRE

Development of new reactivators of OP-inhibited cholinesterases – Ludovic JEAN

Risk-Informed Demand for CBRN Medical Countermeasures – Mark Lawrence JOHNSON

Response of Human Lung Cells Exposed to Sulfur Mustard: a Multiparametric Analysis – Petr JOST

Innovative antiviral strategies targeting different steps of RABV infection – Sabrina KALI

Synthesis of Functionalized Chitosan Nanoparticles for Plutonium Pulmonary Decorporation – Laurane LEOST

Efficiency of phage therapy in an acute murine model of pulmonary infection – Guillaume L'HOSTIS

Immunopurification of proteins modified on tyrosine by chlorpyrifos oxon – Oksana LOCKRIDGE

High-Throughput Screening of Rac1 modulators as regulators of innate and acquired immunity – Nassim MAHTAL

Assessment of new medical countermeasures against nerve agent poisoning using an isolated organ approach –Katharina MARQUART

Bone Marrow Selective Shielding as an Approach to Protect First Responders from Deterministic and Stochastic Radiation Effects – Oren MILSTEIN

Influence of structure of acetylcholinesterase reactivators on their cytotoxicity – Lubica MUCKOVA

Acetylcholinesterase and respiration: where this essential enzyme is required? – Aurélie NERVO

Quorum quenching lactonase: towards innovative medical countermeasures against bacterial infections –
Laure PLENER

Hupresin, a new affinity resin to purify butyrylcholinesterase – Benoît ROUBINET

Early detection of active edema and lethal factors during cutaneous and pulmonary anthrax –
Clémence ROUGEAUX

Quantification of radiological threat and exposure: How much is too much? – Jozef SABOL

Using phenothiazines to inhibit efflux pumps: impact on B. pseudomallei clinical isolats – Marine SCHNETTERLE

Integrin CD11c as an emerging biomarker for Anthrax Edema Toxin infection – Emilie TESSIER


Protection/Decontamination


In vitro hair and skin decontamination studies evaluating the ladder pipe decontamination system (LPS), dry decontamination and combined dry and LPS decontamination strategies – Nevine AMER

Development of an in vitro combined human hair and pig skin model for evaluation of emergency decontamination strategies – Nevine AMER

Mass casualty decontamination in chemical incidents: outcomes from a series of human volunteer trials –
Richard AMLÔT

Volunteer trials of a novel improvised dry decontamination protocol for mass casualty incidents as part of the UK’s Initial Operational Response – Richard AMLÔT

Laboratory-based studies of absorbent materials for mass casualty decontamination as part of the UK’s Initial Operational Response – Robert CHILCOTT

Formulating enzymes towards broad spectrum decontamination of chemical warfare agents (H, G and V) –
David DAUDE

Experimental characterization of DEC’POL® decontamination properties (New emergency decontamination mitt) on threats agents simulants – Carole DOUGNAC

Optimisation of non-ambulant (clinical) decontamination processes – Adam DURRANT

Can sol-gel materials replace activated carbon? – Eva GRINENVAL

An environmentally friendly approach to extracting specifically uranium from contaminated soils and water –
Miryana HEMADI

Adaptation of civilian system “Field and Laboratory Emission Cell FLEC®”; for the measurement of CWA vapors released by solid materials after a decontamination process – Aurélie JACQUART

Emerging Concepts in Decontamination – Jaromy JESSOP

Field trial of a putatively optimised process for ladder pipe decontamination of mass casualties – Joanne LARNER

BioChemGEL-Sys® B&C decontamination of Infrastructures – Célia LEPEYTRE

A combined skin and hair model for assessing decontamination systems using human volunteers
Devanya MAHALINGAM

Evaluation of the ladder pipe system for mass casualty decontamination studies: in vitro studies with the chemical warfare agents sulphur mustard and VX – Hazem MATAR

Design issues and user feedback for Hospital CBRN decontamination unit – Michel PHILIPS

In vitro skin decontamination effectiveness as a function of contaminant geometry – Andreia PINHAL

In vitro skin decontamination effectiveness as a function of contamination density – Andreia PINHAL

Assessment of hair contamination by chemical warfare agents and evaluation of common decontamination procedures towards hair – Anne PIRAM

Development of a new animal model for evaluating toxicity and growth disruption: the case of organophosphorus compounds – Laetitia POIRIER

Harnessing a versatile lactonase from Sulfolobus solfataricus for health, protection and biodecontamination – Benjamin REMY

Fuller’s earth physical chemistry: mechanisms of action – Annick ROUL

Formulation of Pickering emulsion stabilized by CeO2, application for skin decontamination of the organophosphorus pesticide Paraoxon – Alicia SALERNO

Using ceria for skin decontamination of the organophosphorus pesticide Paraoxon: impact of physico-chemical properties of CeO2 and galenic form on its degradation activity – Alicia SALERNO

Metal-organic frameworks for C-protective clothing and respiratory cartridges – Frank SCHNÜRER

Decontamination of a small group of people – Jean-Christophe ZINK

Decontamination of working dog – Jean-Christophe ZINK


Detection


PathoTRACK: Toward a complete analytical chain of NGS data for the detection and identification of pathogenic organisms – Johann BEGHAIN

Particles sampling for explosives detection with the prototype device SYMOPREP – Alain BRY

Hair absorption of organophosphorus nerve agent simulants – Clémentine COTE

High-throughput DNA sequencing and bioinformatics for the detection and identification of pathogenic organisms in complex mixtures – Stéphane CRUVEILLER

Automated analytical system for sensitive detection of bacterial spores – Remco den DULK

Development of a Field-Forward Kit Designed to Extract Nerve Agent Breakdown Compounds from Urine and Aqueous Environmental Samples – Robert diTARGIANI

Gadosphere: a Gd-based plastic detector for wide spectrum neutron detection – Jonathan DUMAZERT

Flat detector of toxic aerosols – Michal DYMAK

Genetic detection of biothreat agents – Fabienne GAS

An innovative microfluidic qPCR platform for high throughput qPCR testing of bioterrorism agents – Fabienne GAS

Rapid absolute quantification of abrin toxin and its isoforms in complex matrices by immuno-extraction and high resolution targeted mass spectrometry – Eva-Maria HANSBAUER

Automatized functional annotation of virulence and resistance factors to complement phylopeptidomics results – Virginie JOUFFRET

Identification and discrimination of bacteria by phylopeptidomics: the Bacillus genus example – Charlotte MAPPA

Identification of antimicrobial resistance biomarkers in Burkhodleria pseudomallei based on whole-cells MALDI-TOF mass spectrometry: from surrogates to clinical strains – Mélissa MARCHANDEAU

Optical elastic scattering for label-free identification of bacterial pathogens – Pierre R. MARCOUX

Experimental material discrimination in spectral tomography – Vincent MOULIN

Multi-energy X-ray detectors to improve air-cargo security – Caroline PAULUS

Detection of Special Nuclear Materials by Neutron Interrogation – Bertrand PEROT

Development of a novel piezoresistive lever sensor for pathogens detection – Laurent PHAM VAN

Mix24X, a reference artificial microbiota to evaluate phylopeptidomics and metaproteomics tools – Olivier PIBLE

Hazardous Material Identification Through Opaque Containers using a Handheld Spatially Offset Raman Spectrometer – Oliver PRESLY

Development of Micro- Time-Of-Flight mass spectrometer for Chemical Threat in situ detection –
Frédéric PROGENT

Selective and sensitive near-infrared fluorescent probe for non phosphonylated acetylcholinesterase imaging – Pierre-Yves RENARD

A simple sample preparation device, keystone of a biological threat detection chain – Jean-Maxime ROUX

The tagged neutron inspection system of the C-BORD project – Alix SARDET

New method development for the fast identification of toxic chemicals by the analysis of their oxidation products – Sébastien SCHRAMM

A whole cell optical bioassay for the detection of chemical warfare agent simulants – Viviana SCOGNAMIGLIO

SPIR-Explorer: a Versatile RAD/NuC payload for UAV/UAG – Julien SPRUYTTE


Risk Management


Psychological well-being of healthcare staff involved in the Ebola Response 2014-2015 – Richard AMLÔT

Improvements and innovative developments in CERES®, the CEA decision support system fitted to noxious atmospheric releases – Patrick ARMAND

French CBRNE medical SOPs: lessons learnt from EU funded FP7 exercises – Catherine BERTRAND

Fitting-out and testing of a FTIR stand-off vehicle – Salvatore CORRAO

Nuclear Risk, from Radioisotope (bio)chemistry to Public Perception – Christophe DEN AUWER

Lessons learned from chemical demonstrations in the European CBRNe EDEN project – Céline DUPUIS

A simple and operative CBRNe taxonomy proposal to facilitate the resilience of Hospital & Skilled Nursing Facility in France in light of the current terrorist threat – Jan-Cedric HANSEN

United Nations Secretary General Mechanism – Lionel KOCH

UPCAST - Unified Platform for CBRN Accident/Attack Scenario Management – Francisco MOITINHO DE ALMEIDA

Inserm Jean Mérieux BSL4 Laboratory : an overview – Delphine PANNETIER

Guidance for the security of hazardous materials (CBRNE) in health care facilities – Pepijn VAN DEN BROEK

 

>> Download the poster session programme in PDF